Can not open in any Microsoft browser

Can not open in any Microsoft browser

I just did new install, changed port to 443 HTTPs. Been setting up, configuring and such in Google Chrome. Just opened in Microsoft Edge browser, and its like server is not even running. I opened up Internet Explorer 11, same thing.

So I opened remote desktop to another machine located outside our own network, and same thing. I can open in Chrome, but not in either Edge or IE. I have recently come across some devices from a manufacturer that limited access to only Microsoft browsers. I would not assume at all Support Center would be configured to limit itself this way, so I am wondering if there is another issue whereby it is not responding to the HTTPS request from these MS browsers.
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