Cannot send mail

Cannot send mail

I am running ADSelfService Plus on a Windows 7 machine.  I have an SMTP server in house and I can telnet to port 25 on that server (Windows 2012) from the Windows 7 command line, however, I cannot send mail from the application.  I have other applications on that system that are able to send mail.  It tells me that is cannot connect to port 25 on that server.  Any ideas?
                New to ADManager Plus?

                  New to ADSelfService Plus?