Is ADManager Plus compatible with DUO for 2-factor authentication?

Is ADManager Plus compatible with DUO for 2-factor authentication?

My company currently uses ADManager Plus to enable remote users to reset their AD password.  It sits behind RSA 2-factor authentication on our VPN.  RSA is currently not integrated with AD.  We are replacing RSA with DUO for 2-factor authentication.  Does ADManager Plus integrate with DUO for 2-factor authentication? 
                New to ADManager Plus?

                  New to ADSelfService Plus?